Medications that can cause a false positive pregnancy test

In this article, Dr. Gleaton shares how pregnancy tests work, what medications could affect pregnancy test results, and when to talk to your doctor.

By OBGYN and fertility expert Dr. Kenosha Gleaton

Taking a pregnancy test can be a nerve-wracking experience, and you want to be confident when reading the results. We’ve already covered the most common questions in our guide to peeing on a stick (POAS), but now it’s time to cover what medications could affect your pregnancy test results. 

How medications affect pregnancy test results

To recap, pregnancy tests work by detecting the pregnancy hormone, hCG, in urine. If the pregnancy test detects a certain level of hCG, it will show a positive result. hCG is made when a fertilized egg implants in the uterus, usually around 10 days after conception, and increases every day in early pregnancy. 

If you’re taking a medication that contains or affects hCG production, it’s possible that you could receive a false pregnancy test result. This means you could receive a positive test without actually being pregnant, or (more rarely) a negative test when you are pregnant. 

What medications may affect pregnancy test results

Most medicines, including over-the-counter and prescription, should not affect the results of a home pregnancy test. But medicines that have the pregnancy hormone hCG in them may give a false positive test result. This includes some medicines given for infertility treatments—often called the “trigger shot” and sold under the brand names Novarel, Ovidrel, Pregnyl, and Profasi.

What to do if you suspect medication is affecting pregnancy test results

If you suspect your medication may be affecting your pregnancy test results, you should consult with your doctor. Your doctor can run a blood test and perform a transvaginal ultrasound to give you a definite answer on whether or not you’re pregnant. 

If you’re on medications for fertility treatments, it’s important you don’t interfere with your medication routine without supervision from your doctor.

Medications that can cause a false positive pregnancy test

When to call your doctor

If you believe you’ve been getting multiple false positives or false negatives, you should see your doctor. This is especially important if you are participating in fertility treatments or are showing symptoms of pregnancy, but receiving negative test results. 

Some false pregnancy test results could be a result of a hormone imbalance, including PCOS, a chemical or ectopic pregnancy, evaporation lines, and more. Make sure you’re following your test instructions correctly to avoid any user error. We made sure our early-result pregnancy tests are simple and easy to use with jargon-free instructions to get the clear answer you need.
 

Follow instructions and know when to seek advice

It’s important to follow directions exactly when taking pregnancy tests, otherwise you could end up with a false positive or false negative result. If you’re following the instructions correctly and you’re still concerned that your results are incorrect, you should consult your doctor. Many fertility medications and occasionally some OTC or prescription drugs could cause a false pregnancy test result, but a blood test and transvaginal ultrasound will help rule this out. 

Featured Image by Pexels

Medications that can cause a false positive pregnancy test

  • Services
    • Pregnancy Testing
    • Ultrasound
    • STI Testing
    • Reproductive Grief Care
    • Abortion Pill Reversal
    • Parenting Program
    • Men’s Services
  • Classes
    • Enrollment
    • Classes
  • Blog
  • Contact Us
  • Give

Menu

Medications that can cause a false positive pregnancy test

Are you doubting the accuracy of your pregnancy test results? Home pregnancy tests are convenient and can quickly be administered, but there are a few variances that could give you an incorrect result.

  • false positive pregnancy test means the test says you are pregnant, but you are NOT. [1]
  • false negative pregnancy test means the test says you are not pregnant, but you ARE.
  • faint line pregnancy test means you may be pregnant, but a more sensitive/accurate test is needed because it may be very early in the pregnancy.

What causes inaccurate pregnancy test results?

  1. Insensitive Pregnancy Test
    Not all home pregnancy tests are created equal, even if the packaging claims 99% accurate results. The manufacturer isn’t telling you that a test is more or less effective depending on how many days past a missed period you are. Pregnancy tests detect the hCG hormone levels in your body – the hormone that your cells secrete to become the placenta. Your hCG levels will increase rapidly after implantation and continue doubling every 2-3 days for the next 10 weeks. [2] Thus, in the early stages of your pregnancy, your hCG levels are at their lowest – and only the most sensitive pregnancy test can accurately detect the first signs of pregnancy. The most sensitive pregnancy test, and most effective at accurately detecting pregnancy earlier, would be one that detects hCG levels at the lowest mIU/ml (in milli-International Units per milliliter of urine). [3] So, a pregnancy test that is advertised as “20 lowest hCG detected”, is more accurate than one advertising 50. If a pregnancy test is showing faint positive lines, this could be the result of a pregnancy test being unable to detect lower hCG levels because it is very early in the pregnancy. Or, it could be a more sensitive pregnancy test triggering false positive lines because of other factors, such as the below.
  2. Improper Testing
    Following the instructions exactly is important for an accurate result reading. Set a timer before reading the results – don’t guess at the elapsed time since you took the test. Being off by 30 seconds could give you a false negative, false positive, or faint line results. Know that testing at least a week after a missed period will provide more accurate results, although this will greatly depend on the lowest hCG levels your pregnancy test can detect. Taking a test in the morning is also helpful, as your urine is more concentrated. Keep in mind that consuming large amounts of water before taking a pregnancy test can alter your results.
  3. Medication Interference
    This is not something you can easily determine without consulting your doctor, but keep in mind it could potentially influence a false positive or negative. Medications that could affect your test include benzodiazepines, phenothiazine, promethazine and others. Urine contaminated with blood or protein can also trigger a false positive. A laboratory-quality test may be your best option for accurate results.
  4. Medical Conditions
    Although very uncommon, it’s still possible to get a false positive because of hCG-producing medical conditions. These could include choriocarcinoma (rare form of cancer usually found in the uterus), breast, ovarian or testicular cancer.
  5. Defective Pregnancy Test
    It’s not common, but it’s not out of the question either. Make sure your home pregnancy test is not expired before using. And if you question the results, even on a non-expired test, it’s okay. Even with the highest quality control, there can be a defective test here or there. Try taking another test from a different batch, or reach out to a local clinic for a laboratory-quality pregnancy test.

False positive and negative results (and faint lines) are not common, but they do happen. If you are unsure of your results, getting a laboratory-quality test is recommended.

If it has been at least 30 days since the first day of your last period, you should consider a lab-quality pregnancy test from a health clinic. At Blue Ridge Women’s Center, our medical staff provide free pregnancy testing. Our lab-quality urine tests can detect pregnancy as early as 7-14 days after conception. 

Sources
[1] http://www.babymed.com/pregnancy-testing/false-positive-pregnancy-test-result
[2] http://www.webmd.com/baby/guide/pregnancy-tests#1
[3] http://www.parentingweekly.com/preconception/preconception_information/home_pregnancy_test_accuracy.htm

Pregnant?

  • (540) 362-4357

  • 5034 Williamson Rd
  • Roanoke, VA 24012

  • 24/7 Help Hotline
  • 1-800-712-HELP
  • Text “HELPLINE” to 313131

Our Mission

Over 50% of all pregnancies are unplanned, leaving many women feeling alone and uncertain of her future. By providing a safe environment to be heard and supported, Blue Ridge Women’s Center equips women to make an informed decision for her and her family.

Our Hours

Monday | 9:30 AM – 4:00 PM
Tuesday | 9:30 AM – 8:00 PM
Wednesday | 9:30 AM – 4:00 PM
Thursday | 9:30 AM – 8:00 PM
Friday  | 9:30 AM – 4:00 PM

Connect With Us

©2021 Blue Ridge Women’s Center,
All Rights Reserved

Blue Ridge Women’s Center does not perform or refer for pregnancy terminations (abortion), but is committed to offering accurate information to empower women to make a fully-informed decision. Our services are not intended to be a substitute for routine or emergency medical care. Individuals who believe they are experiencing a medical emergency should call 9-1-1 and seek care from the nearest emergency room.

What medicines cause false positive pregnancy test?

Other medications can also cause false-positive pregnancy tests. They include but aren't limited to: anti-anxiety medications, like diazepam (Valium) or alprazolam (Xanax) antipsychotics, such as clozapine or chlorpromazine..
Novarel..
Pregnyl..
Ovidrel..
Profasi..

What medications affect hCG levels?

Medications that could affect your test include benzodiazepines, phenothiazine, promethazine and others. Urine contaminated with blood or protein can also trigger a false positive. A laboratory-quality test may be your best option for accurate results.

Can anything else trigger a positive pregnancy test?

A test will only show a false positive if you have hCG in your system for another reason such as you were recently pregnant, are taking fertility medications containing hCG, or if you have a medical condition, like some rare ovarian cysts.

Do any medications interfere with pregnancy test?

Most medicines, including over-the-counter and prescription, should not affect the results of a home pregnancy test. But medicines that have the pregnancy hormone hCG in them may give a false positive test result.